Figure 3.

Glucose tolerance after glucose injection was increased by EB in WT and HFD-fed KIKO female mice. GTT data from (A) WT, (B) KIKO, and (C) KO female mice. Data were analyzed by repeated-measures, 2-way ANOVA with post hoc Newman-Keuls test. (D) Area under the curve analysis (mg/dL/min). Data were analyzed by a multifactorial ANOVA with post hoc Newman-Keuls test. Sample sizes were 9 to 10 per group. For A, B, and C, letters denote an effect of steroid and underlined letters denote an effect of diet. For D, capped lines denote comparisons within genotype between steroid (oil vs EB) and diet (LFD vs HFD) combinations, and underlined letters denote comparisons between WT and either KIKO or KO within the same treatment combination (a, P < 0.05; b, P < 0.01; c, P < 0.001; d, P < 0.0001).