Figure 2.

GnRH neuron activity is elevated and similar during the estradiol-induced daily surge and preovulatory proestrous surge. (A) Representative firing patterns for GnRH neurons recorded from diestrous (left), proestrous (middle), and OVX+E mice (right). (B) Individual values for mean firing rate and percentage of quiescence in GnRH neurons from diestrous (open circles), proestrous (black circles), and OVX+E (gray circles) mice. Each symbol represents 1 mouse; means ± standard error of means are shown by the horizontal and vertical lines, respectively. *P < 0.05 calculated by Kruskal-Wallis/Dunn test.