Table 2.
Exposure | Outcome | Fat Mass
z Scorea |
Waist
Circumference z Score |
BMI
z Score |
Obesity |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coefficient | 95% CI | P | Coefficient | 95% CI | P | Coefficient | 95% CI | P | OR | 95% CI | P | ||
Leptin, per 10 pg/mL | Model 1 | 0.07 | 0.04, 0.10 | <0.001 | 0.08 | 0.05, 0.12 | <0.001 | 0.11 | 0.07, 0.15 | <0.001 | 1.15 | 1.00, 1.31 | 0.046 |
Model 2 | 0.04 | 0.00, 0.07 | 0.023 | 0.05 | 0.01, 0.08 | 0.008 | 0.06 | 0.02, 0.10 | 0.003 | 1.00 | 0.85, 1.17 | 0.993 | |
Model 3 | 0.03 | 0.00, 0.06 | 0.086 | 0.04 | 0.00, 0.07 | 0.045 | 0.04 | 0.00, 0.08 | 0.029 | 0.95 | 0.81, 1.12 | 0.548 | |
Adiponectin, per 10 µg/mL | Model 1 | 0.00 | −0.01, 0.01 | 0.828 | −0.01 | −0.02, 0.00 | 0.072 | 0.00 | −0.02, 0.01 | 0.602 | 0.99 | 0.94, 1.05 | 0.845 |
Model 2 | 0.00 | −0.01, 0.01 | 0.916 | −0.01 | −0.02, 0.00 | 0.118 | 0.00 | −0.01, 0.01 | 0.858 | 1.00 | 0.94, 1.05 | 0.874 | |
Model 3 | 0.00 | −0.01, 0.01 | 0.875 | −0.01 | −0.02, 0.00 | 0.100 | 0.00 | −0.01, 0.01 | 0.767 | 0.99 | 0.94, 1.05 | 0.834 | |
Birth weight, per 100 gb | Model 1 | 0.01 | 0.00, 0.02 | 0.006 | 0.03 | 0.03, 0.04 | <0.001 | 0.04 | 0.03, 0.05 | <0.001 | 1.06 | 1.02, 1.10 | 0.006 |
Model 2 | 0.00 | 0.00, 0.01 | 0.192 | 0.03 | 0.02, 0.04 | <0.001 | 0.04 | 0.03, 0.04 | <0.001 | 1.03 | 0.99, 1.07 | 0.193 | |
Model 3 | 0.00 | −0.01, 0.01 | 0.741 | 0.02 | 0.02, 0.03 | <0.001 | 0.03 | 0.02, 0.04 | <0.001 | 1.01 | 0.96, 1.05 | 0.852 |
For this study, N= 2775. Model 1 was adjusted for offspring sex and age at measurement. Model 2 was adjusted for offspring sex, age at measurement, and maternal confounders (age, smoking, parity, occupational social class, education, and prepregnancy BMI). Model 3 was adjusted for offspring sex, age at measurement, and maternal confounders plus pregnancy confounders (gestational age at birth, mode of delivery, gestational weight gain, hypertensive disorders, and diabetic disorders of pregnancy).
Abbreviations: CI, confidence interval; OR, odds ratio.
Fat mass adjusted for height.
Birth weight adjusted for sex, gestational age, and singleton/twin pregnancy.