Table. 1.
Effect of topical application of gentamicin (8 mg kg-1), AgNPs (0.08 mg kg-1), AgNPs (0.04 mg kg-1) and AgNPs (0.02 mg kg-1) on wound area (mm2). Data are presented as mean ± SEM
| Groups | Wound area (%wound contraction ) | |||
|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 21 | |
| Control | 12.56 | 11.05 ± 0.15 (11.39) | 6.43 ± 0.18 (48.59) | 1.54 ± 0.25 (87.11) |
| Gentamicin | 12.56 | 9.66 ± 0.15 (23.00) | 2.67 ± 0.18 (78.94) | 0.00 ± 0.25 (99.86) |
| AgNPs (0.08 mg kg -1 ) | 12.56 | 8.57 ± 0.15 (31.81)* | 3.20 ± 0.19 (74.75) | 0.11 ± 0.26 (99.93)* |
| AgNPs (0.04 mg kg -1 ) | 12.56 | 9.97 ± 0.15 (20.52) | 4.57 ± 0.18 (64.29) | 0.13 ± 0.25 (98.70) |
| AgNps (0.02 mg kg -1 ) | 12.56 | 10.50 ± 0.15 (16.28) | 5.66 ± 0.18 (53.78) | 1.22 ± 0.25 (89.92) |
*
The percentage of wound was contraction compared with day 0 is provided within the parentheses. Asterisks denote p-value significance comparing AgNPs 0.08 mg kg-1 to the other groups (p < 0.0001).