Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May 1;214(5):1297–1311. doi: 10.1084/jem.20161141

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Choo et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Spore-initiated infection results in higher BA burdens and milder inflammatory responses than VB-initiated infection. (A) Mice were infected with BA (10⁷ cfu per host) by footpad injection of VB or spores (Sp). Host survival (n = 10–15 mice/group) was monitored for 10 d. (B–D) Mice were infected with BA (2.5 × 10⁶ cfu per host) by footpad injection of VB or Sp. Bacterial burdens in popliteal lymph nodes were determined (B) and neutrophil infiltration in footpad skin was analyzed by flow cytometry (C) 3 d after infection. Footpad swelling (n = 4 mice/group) was determined daily for 3 d (D). Data are representative of two experiments (A, B, and D) or four animals (C) with similar results. *, P < 0.05; **, P < 0.01; Log-rank test (A) and Student’s t test (B).