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. Author manuscript; available in PMC: 2017 Jul 20.
Published in final edited form as: Int J Obes (Lond). 2017 Jan 20;41(5):739–749. doi: 10.1038/ijo.2017.16

Figure 2. CAP increases PPARs and thermogenic BMP8b and UCP-1 in BAT of WT but not TRPV1−/− mice.

Figure 2

A. PPARα and PPARγ expression in BAT obtained from NCD or HFD (± CAP)-fed WT and TRPV1−/− mice. B. Mean PPAR proteins expression intensity ± S.E.M normalized to GAPDH (loading control) for n = 5 independent experiments. The average mRNA levels ± S.E.M of pparα (C) and pparγ (D) normalized to NCD are given for NCD, HFD or HFD + CAP-fed WT and TRPV1−/− mice. E. BMP8b and UCP-1 expression in BAT obtained from NCD or HFD (± CAP)-fed WT and TRPV1−/− mice. F. BMP8b and UCP-1 protein expression mean band intensities ± S.E.M normalized to the loading control GAPDH for 5 independent experiments. The mean mRNA levels ± S.E.M of bmp8b (G) and ucp-1 (H) normalized to NCD are given for NCD, HFD or HFD + CAP-fed WT and TRPV1−/− mice. For quantitative RT-PCR experiments, 18S ribosomal RNA was used as control. $$ and ** represent statistical significance for P<0.05.