Table 1.
Cohort characteristics
| Female | Male | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Anorexia nervosa | No eating disorder | P | Anorexia nervosa | No eating disorder | P | |
| N | 9239 | 92,329 | 556 | 5560 | ||
| Age at start of observation, yearsa | 29.8 (22.8–38.6) | 29.8 (22.8–38.8) | 30.2 (22.1, 40.2) | 30.2 (21.8, 40.5) | ||
| Calendar year at start of observationa | 2005 (2001, 2008) | 2005 (2001, 2008) | 2004 (2001, 2008) | 2004 (2001, 2008) | ||
| Age at diagnosis, yearsa | 19.0 (16.0–24.0) | N/A | 19.5 (15.7, 25.0) | N/A | ||
| Country | ||||||
| England | 7474 (80.9%) | 74,687 (80.9%) | 454 (81.7%) | 4540 (81.7%) | ||
| Ireland | 253 (2.7%) | 2530 (2.7%) | 14 (2.5%) | 140 (2.5%) | ||
| Scotland | 987 (10.7%) | 9862 (10.7%) | 58 (10.4%) | 580 (10.4%) | ||
| Wales | 525 (5.7%) | 5250 (5.7%) | 30 (5.4%) | 300 (5.4%) | ||
| Observation time, yearsa | 3.4 (1.3, 7.0) | 3.7 (1.5, 7.3) | <0.001 | 3.5 (1.4, 7.3) | 4.0 (1.6, 7.9) | 0.06 |
| Body mass indexa,b | 20.0 (17.9–22.3) | 24.0 (21.4–28.2) | <0.001 | 21.4 (18.3, 24.2) | 25.9 (22.7, 29.1) | <0.001 |
| History of prior fracture | 1615 (17.5%) | 11,946 (12.9%) | <0.001 | 145 (26.1%) | 1381 (24.8%) | 0.52 |
| Anti-depressant use | 2942 (31.8%) | 11,924 (12.9%) | <0.001 | 151 (27.2%) | 352 (6.3%) | <0.001 |
| Alcohol abuse | 196 (2.1%) | 383 (0.4%) | <0.001 | 18 (3.2%) | 47 (0.9%) | <0.001 |
a
Median (inter-quartile range),
b
N=5994 for anorexia nervosa and 38,312 for no eating disorder