Table 3.
Age-adjusted hazard ratio (HR) for fracture associated with anorexia nervosa in females versus males
| Site | Number of events | Females | Males | |||
|---|---|---|---|---|---|---|
|
| ||||||
| Females | Males | HR (95% CI) | P | HR (95% CI) | P | |
| Vertebra | 98 | 5 | 2.19 (1.30, 3.69) | 0.003 | 7.25 (1.21, 43.45) | 0.03 |
| Skull/face | 139 | 36 | 2.15 (1.39, 3.34) | 0.001 | 0.30 (0.04, 2.18) | 0.23 |
| Pelvis | 46 | 1 | 4.54 (2.42, 8.50) | <0.001 | ----- | ----- |
| Rib/thorax | 130 | 15 | 2.87 (1.89, 4.36) | <0.001 | 1.67 (0.38, 7.42) | 0.50 |
| Clavicle/scapula | 114 | 34 | 2.20 (1.36, 3.57) | 0.001 | 0.32 (0.04, 2.32) | 0.26 |
| Humerus/elbow | 244 | 17 | 2.17 (1.56, 3.02) | <0.001 | 1.39 (0.32, 6.10) | 0.66 |
| Forearm/wrist | 736 | 46 | 1.49 (1.19, 1.85) | <0.001 | 0.74 (0.23, 2.40) | 0.62 |
| Hand | 657 | 124 | 1.40 (1.11, 1.78) | 0.005 | 0.73 (0.35, 1.49) | 0.38 |
| Hip/femur | 72 | 7 | 5.59 (3.44, 9.09) | <0.001 | 1.89 (0.23, 15.74) | 0.56 |
| Lower leg/ankle | 554 | 48 | 1.28 (0.98, 1.68) | 0.07 | 0.71 (0.22, 2.28) | 0.57 |
| Foot | 714 | 62 | 1.36 (1.08, 1.71) | 0.008 | 1.81 (0.89, 3.67) | 0.10 |
| Multiple sites | 11 | 1 | 3.89 (1.03, 14.67) | 0.045 | ----- | ----- |
| Not specified | 723 | 57 | 1.91 (1.56, 2.33) | <0.001 | 1.26 (0.54, 2.94) | 0.59 |
| Overall | 3589 | 373 | 1.59 (1.45, 1.75) | <0.001 | 1.05 (0.74, 1.49) | 0.80 |