Table 4.
Association between PNI and lethal prostate cancer in the Swedish Watchful Waiting Cohort and US Health Professionals Follow-Up Study
| Lethal Prostate Cancer |
Crude OR/HRa (95% CI) |
Multivariate |
||
|---|---|---|---|---|
| Model 1b | Model 2c | |||
| Swedish Cohort | ||||
| No PNI | 194/572 (34%) | Ref. | Ref. | Ref. |
| PNI | 34/43 (79%) | 7.4 (3.6, 16.6) | 2.0 (0.8, 4.9) | 1.9 (0.8, 5.1) |
| HPFS | ||||
| No PNI | 29/479 (6%) | Ref. | Ref. | Ref. |
| PNI | 58/370 (16%) | 3.1 (2.0, 4.9) | 1.8 (1.1, 3.0) | 1.8 (1.0, 3.3) |
a
Odds ratios (OR) and hazard ratios (HR) used as measures of association for the Swedish Cohort and HPFS, respectively;
b
adjusted for age and Gleason grade;
c
additionally adjusted for tumor volume (Swedish cohort), and pathologic tumor stage (HPFS); CI confidence interval