Table 5.
Prostate tumor biomarkers by PNI status in the Health Professionals Follow-Up Study. Measures expressed as medians (interquartile range).
| PNI | No PNI | p-value | |
|---|---|---|---|
| TUNEL | 0.5 (0, 2.0) | 0.5 (0, 2.0) | 0.45 |
| Ki67 | 0.2% (0%, 0.6%) | 0.1% (0, 0.5%) | 0.61 |
| Microvessel densitya | 75 (58, 100) | 64 (48, 95) | 0.008 |
| Vessel diameterb (µm) | 22.9 (20.1, 26.1) | 25.6 (22.5, 29.2) | <0.001 |
| Vessel areab (µm2) | 414 (302, 574) | 520 (399, 716) | <0.001 |
| Vessel lumen regularitya | 4.1 (3.3, 4.8) | 3.9 (3.1, 4.7) | 0.17 |
a
Higher values indicate increased tumor angiogenesis;
b
lower values indicate increased tumor angiogenesis