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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Drug Discov Today. 2016 Dec 23;22(4):665–680. doi: 10.1016/j.drudis.2016.12.009

Figure 3.

Figure 3

In vivo antitumor efficacy assay. (a) Tumor volumes of tumor-bearing mice as a function of time (day). The arrows indicate the time points of the drug injection. (b) Tumor-bearing mice at the end of the tests (the 20th day post-treatment) imaged by the IFLUOR™ in vivo imaging system (inset: excised tumor tissues after imaging). Paclitaxel (PTX)-hyaluronic acid (HA)-ss- deoxycholic acid (DOCA) micelles (iv) exhibited the highest tumor growth inhibition efficacy compared with saline (i), Taxol® (ii) and PTX-HA-DOCA micelles (iii). Reproduced, with permission from [65].