Table 5.
Comparative summary of prevalence and direction of association for risk factors among the different subpopulations.
| Risk Factorsa | Prevalence of Risk Factors Among Cases | Direction of Association With Breast Cancer Risk | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||||
| US | Mexico | US | Mexico | |||||||
|
|
|
|
|
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| NHW | Hispanic 0–43% | Hispanic 43.1–100% | 0–68% | 68.1–100% | NHW | Hispanic 0–43% | Hispanic 43.1–100% | 0–68% | 68.1–100% | |
| Family history of breast cancerc,d | 23.1% | 23.2% | 16.0% | 8.9% | 4.2% | Increase | Increase | Increase | Increase | Increase |
| Few births/Later age at first birth (<3 births and/or >25 y)b,d | 65.1% | 56.9% | 49.3% | 57.2% | 47.4% | Increasef | Increasef | Increase | Increase | Increasef |
| No Breast-feedinge | 47.4% | 47.4% | 47.9% | 26.7% | 19.5% | Increasef | Increasef | Increasef | Increase | |
| Higher body mass index (≥25kg/m2)b,c,e | 60.1% | 71.0% | 83.0% | 81.8% | 86.8% | Decrease | Decrease | |||
| Earlier age at menarche (≤11 y)b,e | 22.6% | 28.4% | 23.4% | 19.5% | 20.0% | Increase | Increasef | Increasef | Increasef | |
| Later age at menopause (>50 y) | 43.9% | 37.9% | 37.6% | 33.1% | 31.1% | Increase | Increase | |||
| Hormone therapy use (Yes)b,c,d,e | 75.4% | 63.3% | 55.0% | 28.0% | 19.0% | Increasef | Increase | Increase | Increase | |
| Alcohol consumption (Any)b,d,e | 53.0% | 33.6% | 28.7% | 19.9% | 12.1% | Increasef | Increase | |||
a
Risk factors were dichotomized (e.g. presence versus absence) as presented.
b
P < 0.05 comparing prevalence among NHW versus US Hispanic (0–43%).
c
P < 0.05 comparing prevalence among US Hispanic (0–43%) versus US Hispanic (43.1–100%).
d
P < 0.05 comparing prevalence among Mexican (0–68%) versus Mexican(68.1–100%).
e
P < 0.05 comparing US Hispanic (0–43%) versus Mexican (0–68%).
f
Associations that were suggestive but not statistically significant.