Figure 1.

B-cell lymphoma (Bcl)-2 and Bcl-X_L and their targets in Ca²⁺ signaling, inositol 1,4,5-trisphosphate receptor (IP₃R) and voltage-dependent anion channel 1 (VDAC1), are present in the mitochondria-associated endoplasmic reticulum membranes (MAMs). Representative immunoblots showing the presence of VDAC1, IP₃Rs, Bcl-2, and Bcl-X_L in the MAMs of MEFs. Calnexin (CNX) and cytochrome c (Cyt c) served as specific MAMs and mitochondrial markers, respectively. These data were originally published in Journal of Biological Chemistry with following reference: Monaco et al. (45). © The American Society for Biochemistry and Molecular Biology. Authors of articles in Journal of Biological Chemistry have the rights to reuse their own material and are automatically granted a permission to reuse figures from their articles in future works. The original results have been produced by Dr. Alex van Vliet in the laboratory of Prof. Patrizia Agostinis (KU Leuven, Belgium).