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. 2017 Apr 26;11:1315–1334. doi: 10.2147/DDDT.S127270

Figure 1.

Figure 1

Figure 1

Schematic presentation of the targeting delivery approach using targeted intranuclear delivery of cytotoxic drug (here, Auger electron emitter 111In) by folate receptor-targeted MNT.

Notes: (A) Auger electron range and the efficiency of Auger electron emitters located inside and outside the cell. (B) MNT module functions.

Abbreviations: DTox, diphtheria toxin translocation domain; FA, folic acid; MNTs, modular nanotransporters; NLS, nuclear localization sequence; PEG, polyethylene glycol.