Table 1.
Values of minimum inhibitory concentration (MIC, expressed in μg/ml) of the C7a, AMB and MCZ and FCZ determined in clinical isolates of Candida spp.
| Strains | Antifungal drugs | Concentrations (μg/mL) | ||
|---|---|---|---|---|
| MIC Range | MIC50 | MIC90 | ||
| All species | C7a | 0.25–4 | 1 | 4 |
| AMB | 0.125–16 | 1 | 1 | |
| MCZ | 0.03–>16 | 0.25 | 4 | |
| FCZ | 0.03–>64 | 1 | >64 | |
| Candida albicans | C7a | 0.25–1 | 0.5 | 1 |
| AMB | 0.5–1 | 1 | 1 | |
| MCZ | 0.03–4 | 0.03 | 0.5 | |
| FCZ | 0.03–>64 | 0.25 | 64 | |
| Candida tropicalis | C7a | 0.5–2 | 1 | 2 |
| AMB | 0.5–2 | 1 | 2 | |
| MCZ | 0.06–8 | 0.5 | 8 | |
| FCZ | 0.25–>64 | 1 | 64 | |
| Candida parapsilosis | C7a | 1–4 | 2 | 4 |
| AMB | 0.5–1 | 1 | 1 | |
| MCZ | 0.06–4 | 0.25 | 4 | |
| FCZ | 0.06–>64 | 1 | 16 | |
| Candida glabrata | C7a | 0.25–4 | 1 | 2 |
| AMB | 0.125–2 | 0.5 | 1 | |
| MCZ | 0.03–16 | 0.03 | 0.5 | |
| FCZ | 0.25–>64 | 2 | 8 | |
| Candida krusei | C7a | 1 | 1 | 1 |
| AMB | 0.5–1 | 0.5 | 1 | |
| MCZ | 2–8 | 4 | 8 | |
| FCZ | 64–>64 | 64 | >64 | |
All species, represents the combination of all clinical isolates in this study.