Table 2.
Cumulative percentage of the minimum fungicidal concentration (MFC) of C7a and AMB determined in clinical isolates of Candida spp.
| Cumulative Percentage of MFC (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MFC (μg/mL) | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | >16 | |
| All species | C7a | 11.5 | 31.2 | 72.2 | 78.7 | 86.9 | 90.2 | 93.5 | 100 | |
| AMB | 13.1 | 67.1 | 83.5 | 86.8 | 86.8 | 86.8 | 100 | |||
| C. albicans | C7a | 41.2 | 88.1 | 100 | ||||||
| AMB | 11.7 | 58.7 | 64.5 | 64.5 | 64.5 | 64.5 | 100 | |||
| C. parapsilosis | C7a | 10 | 10 | 50 | 70 | 90 | 100 | |||
| AMB | 10 | 40 | 90 | 100 | ||||||
| C. tropicalis | C7a | 16.6 | 66.6 | 91.6 | 91.6 | 91.6 | 91.6 | 100 | ||
| AMB | 83.3 | 83.3 | 83.3 | 83.3 | 83.3 | 100 | ||||
| C. glabrata | C7a | 18.1 | 81.7 | 81.7 | 90.7 | 90.7 | 90.7 | 100 | ||
| AMB | 9 | 72.6 | 90.7 | 100 | ||||||
| C. krusei | C7a | 0 | 81.8 | 90.8 | 90.8 | 90.8 | 90.8 | 100 | ||
| AMB | 36.3 | 81.7 | 100 | |||||||
Results represent the percentage of isolates showing total growth inhibition at each compound concentration.All species, represents the combination of all clinical isolates in this study.