Table 1.
Non-synonymous amino acid changes that distinguish CHIKV sequences from the Americas from other closely related Asian genotype sequences (American Samoa 2014, Philippines 2013, Micronesia 2013).
| Gene | Nt change | AA change | Sequence ID | Country (year) |
|---|---|---|---|---|
| Capsid | T7735 C | 56 V → A | 14.03985 | Barbados (2014) |
| C8158T | 197 S → L | 14.01349 | St. Lucia (2014) | |
| E2 | C8824T | 94 T → I | KR046233.1 | Trinidad (2014) |
| T8881C | 113 V → A | 14.00309 | BVI (2014) | |
| KJ451624.1 | BVI (2014) | |||
| CH0008 | Mexico (2014) | |||
| CH0045 | Mexico (2014) | |||
| CH0072 | Mexico (2014) | |||
| LI0036 | Mexico (2014) | |||
| TA0006 | Mexico (2014) | |||
| T9646C | 368 V → A | All | All | |
| 6K | C9870A | 20 L → M | All | All |
| T9909A | 33 C → S | 14.03985 | Barbados (2014) | |
| E1 | C10219T | 101 T → M | KR559491 | Colombia (2014) |
| G10452A | 153 A → T | KR559497 | St. Barts 2014) | |
| 14.04425 | Barbados (2014) | |||
| C10498T | 168 S → L | 14.06638 | Trinidad (2014) | |
| T10867C | 291 V → A | 14.01152 | St. Kitts (2014) | |
| A10890T | 299 M → L | 14.03985 | Barbados (2014) | |
| nsP1 | G590A | 171 R → Q | 14.02961 | Bahamas (2014) |
| 14.02086 | Guyana (2014) | |||
| G603A | 176 V → I | 14.0444 | Suriname (2014) | |
| G765A | 230 G → R | 14.0444 | Suriname (2014) | |
| T775A | 233 L → Q | KR046230.1 | Trinidad (2014) | |
| nsP2 | C3389T | 569 R → C | KR046232.1 | Trinidad (2014) |
| C2416T | 245 P → L | 14.0444 | Suriname (2014) | |
| G2481T | 267 A → S | 14.02086 | Guyana (2014) | |
| C1932A | H644Q | KP164571 | Brazil (2014) | |
| nsP3 | G4430A | 118 G → R | 14.01526 | Antigua (2014) |
| T5646C | 521 stop → R | 14.05081 | Cayman Is (2014) | |
| 14.02961 | Bahamas (2014) | |||
| 14.05085 | Cayman Is (2014) | |||
| 14.01507 | Haiti (2014) | |||
| 14.04561 | Jamaica (2014) | |||
| 14.06350 | Suriname (2014) | |||
| CNR20235H | Saint Martin (2013) | |||
| nsP4 | G5962A | 99 R → Q | 14.0444 | Suriname (2014) |
| KR046233.1 | Trinidad (2014) | |||
| 14.02086 | Guyana (2014) | |||
| KR559490.1 | Guyana (2014) | |||
| KR559496.1 | Guyana (2014) | |||
| C6201T | 179 H → Y | 14.06638 | Trinidad (2014) | |
| 14.02346 | St. Vincent (2014) | |||
| 14.03562 | Grenada (2014) | |||
| 14.0256 | Grenada (2014) | |||
| G6762A | 366 A → T | 14.05085 | Cayman Is (2014) | |
| C7276T | 537 A → V | 14.02961 | Bahamas (2014) |
Nucleotide positions are numbered beginning at the start codon for the complete coding sequence; amino acid positions are numbered from the first amino acid of each gene product.