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Proportions of patients who were initial nonresponders over weeks 1–4 (month 1) who became composite responders over weeks 1–12 and 1–26: pooled analysis of Phase 3 studies. Composite response is based on daily improvement of ≥30% in worst abdominal pain score compared with average baseline pain and, on the same day, a Bristol Stool Form Scale score of <5, on ≥50% of treatment days.
