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Proportions of composite responders over weeks 1–4 (month 1) who remained responders over 3 or 5 out of the subsequent 5 months: pooled analysis of Phase 3 studies. Composite response is based on daily improvement of ≥30% in worst abdominal pain score compared with average baseline pain and, on the same day, a Bristol Stool Form Scale score of <5, on ≥50% of treatment days.
