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. 2017 Mar 22;45(10):1319–1328. doi: 10.1111/apt.14031

Figure 8.

Figure 8

Proportions of weeks 1–4 composite nonresponders who were AR responders over weeks 1–4: pooled analysis of Phase 3 studies. Composite response is based on daily improvement of ≥30% in worst abdominal pain score compared with average baseline pain and, on the same day, a Bristol Stool Form Scale score of <5, on ≥50% of treatment days. AR response is defined as a ‘yes’ response to the following question: ‘Over the past week, have you had AR of your IBS symptoms?’. AR, adequate relief; IBS, irritable bowel syndrome.