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. 2017 Mar 6;114(6):1264–1274. doi: 10.1002/bit.26265

Figure 9.

Figure 9

Change in percent aggregate levels over time for drug substance generated from HCCF held in the absence of cystine (0 mM) or in the presence of 0.8 mM cystine per gram mAb at (a) 2–8°C for 17 months (b) 25°C for 1 month (c) 40°C for 1 month.