Table 2.
AQP4 immunogold labeling density along pericapillary and parenchymal astrocytic membrane domains in humans and mice
| Capillaries (n) | Endfoot membrane facing endothelial cell | Endfoot membrane facing pericyte | Parenchymal membrane | Polarization towards endothelial cells (perivascular/parenchymal) | Polarization toward pericytes (perivascular/parenchymal) | |
|---|---|---|---|---|---|---|
| Humans (ID) | ||||||
| 3 | 2 | 31.2 ± 6.4 (4) | ‐ | 16.1 ± 7.0 (4) | 1.9 | ‐ |
| 4 | 9 | 20.9 ± 6.3 (34) | 24.7 ± 6.4 (15) | 6.3 ± 2.6 (42) | 3.3 | 3.9 |
| 5 | 2 | 23.4 ± 3.6 (9) | 23.1 ± 4.9 (5) | 10.2 ± 4.0 (15) | 2.3 | 2.3 |
| 6 | 3 | 26.8 ± 5.8 (12) | 31.2 ± 2.5 (4) | 17.2 ± 5.2 (12) | 1.6 | 1.8 |
| 7 | 1 | 34.3 ± 5.3 (5) | 35.9 ± 6.1 (7) | 17.0 ± 5.3 (9) | 2.0 | 2.1 |
| 8 | 2 | 23.7 ± 5.0 (9) | 19.5 (1) | 8.7 ± 3.0 (6) | 2.7 | 2.2 |
| 9 | 4 | 27.7 ± 4.4 (17) | 31.8 ± 5.3 (10) | 14.2 ± 6.6 (14) | 2.0 | 2.2 |
| 10 | 5 | 20.2 ± 5.5 (26) | 23.5 ± 5.0 (5) | 9.2 ± 3.4 (7) | 2.2 | 2.6 |
| 11 | 5 | 20.8 ± 6.1 (18) | 22.8 ± 4.6 (4) | 11.0 ± 4.6 (15) | 1.9 | 2.1 |
| Mean ± STD | 25.4 ± 4.9 | 26.6 ± 5.7 | 12.2 ± 4.0 | 2.2 ± 0.5 | 2.4 ± 0.7 | |
| Mice | ||||||
| 1 | 4 | 34.5 ± 7.9 (7) | 32.1 ± 6.9 (13) | 5.4 ± 6.7 (16) | 6.4 | 6.0 |
| 2 | 4 | 27.5 ± 10.6 (17) | 31.5 ± 10.0 (5) | 3.0 ± 4.0 (21) | 9.3 | 10.6 |
| 3 | 8 | 29.6 ± 10.5 (41) | 31.7 ± 12.3 (12) | 6.4 ± 5.6 (30) | 4.6 | 5.0 |
| 4 | 2 | 36.4 ± 10.9 (10) | 38.8 ± 10.4 (8) | 6.7 ± 1.4 (5) | 5.4 | 5.8 |
| 5 | 8 | 32.6 ± 7.8 (20) | 32.9 ± 5.0 (9) | 2.9 ± 3.6 (20) | 11.4 | 11.5 |
| Mean ± STD | 32.1 ± 3.6 | 33.4 ± 3.1 | 4.9 ± 1.8 | 7.4 ± 2.9 | 7.8 ± 3.0 |
ID is the identity code of the human subjects. Data presented as mean ± STD with number of observations in parenthesis.