The TLR repertoires of 76 teleosts mapped onto a time-calibrated species phylogeny. All TLRs characterized in the new 66 teleost genomes as well as in 10 reference teleosts genomes (Ensembl and GenBank) mapped onto a species phylogeny generated by Malmstrom et al. The phylogeny demonstrates the loss of MHCII 110–64 Ma (branch range time, black star) reported by Malmstrom et al. Lineage-specific TLR losses are marked by black circles (Gadinae TLR1/2, Paracanthopterygii TLR5 and TLR21beta). The individual species' repertoires are depicted with boxes where the coloration represents the number of copies of each individual TLR. The six major TLR families: TLR1-family, TLR3-family, TLR4-family, TLR5-family, TLR7-family and TLR11-family are indicated with black bars underneath the TLR names. See the electronic supplementary material, table S1 for copy number details. For TLR1/2, a gradient-filled box indicates the presences of either TLR1 or TLR2. The Paracanthopterygiian lineage, Gadiformes order and Gadinae family display shaded grey backgrounds.