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. Author manuscript; available in PMC: 2017 May 3.
Published in final edited form as: Nat Rev Rheumatol. 2014 Dec 23;11(4):206–212. doi: 10.1038/nrrheum.2014.200

Figure 1.

Figure 1

Identification and stem-cell-like properties of CSPCs. CSPCs have been observed in human, equine54 and bovine11 articular cartilage. Identification, isolation and characterization of CSPCs have been based on a | expression of stem-cell-related surface markers (individually and in combination, under various conditions) and b | properties such as clonogenicity and multipotency.6,7,8 Migratory activity of CSPCs has also been found in response to injury31 and in late-stage OA cartilage.32 Abbreviations: CSPC, cartilage stem/progenitor cell; OA, osteoarthritis.