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. 2017 Apr 25;8:15130. doi: 10.1038/ncomms15130

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Copyright © 2017, The Author(s)

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(a) Molecular structure of GSH and CR₉. (b) Scheme of the preparation of positively charged GNCs. (c) Scheme of the preparation of GNC–siRNA complex. The negatively charged siRNA was condensed onto cationic GNCs by electrostatic interaction. (d) The appearance of GNC solution. (e) Excitation and emission spectrum of GNCs. (f) Surface charge of GNCs. Mean±s.d. (n=16). (g) CryoTEM images of GNCs. (h) Diameter of the prepared GNCs. Mean±s.d. (n=120). (i) CryoTEM images of the GNC–siRNA complex. (j) Diameter of the GNC–siRNA complex. Mean±s.d. (n=30). Scale bars, 10 nm.