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. 2017 Jan 25;4(1):ofw219. doi: 10.1093/ofid/ofw219

Table 3.

Associations Between ART Deferral, CD4+ T-Cell Count, and Key-at-Risk Population Among ART-Prescribing Physicians (N = 214) in Malaysia (June–December 2013)

Characteristic Key-at-Risk Population* Clinical Scenario
CD4 ≤50 (CD4 = 17)
AIDS-Defining Condition
CD4 ≤200 (CD4 = 176)
AIDS-Defining Condition
CD4 ≤350 (CD4 = 305)
2010 Guidelines
CD4 ≤500 (CD4 = 470)
2013 Guidelines
AOR (95% CI) P Value AOR (95% CI) P Value AOR (95% CI) P
Value
AOR (95% CI) P Value
Substance use Injects or uses drugs 18.9 (9.8–36.5) <.0001 14.5 (8.6– 24.6) <.0001 6.9 (4.8– 9.9) <.0001 2.0 (1.4– 2.7) <.0001
Consumes alcohol 16.5 (8.3– 33.1) <.0001 11.4 (6.7– 19.5) <.0001 5.9 (4.2– 8.3) <.0001 3.4 (2.3– 5.1) <.0001
Currently receives MMT 2.9 (1.5– 5.7) .0022 1.9 (1.2– 2.9) .0020 2.0 (1.5– 2.5) <.0001 1.6 (1.3– 2.1) <.0001
Social situation Recently released from prison 12.3 (6.3– 24.1) <.0001 8.4 (5.0– 14.0) <.0001 5.1 (3.6– 7.1) <.0001 2.6 (1.9– 3.7) <.0001
Lives alone and not with family 8.3 (4.3– 16.0) <.0001 5.5 (3.3– 9.1) <.0001 3.5 (2.5– 4.7) <.0001 2.2 (1.6– 3.1) <.0001
Has HIV-uninfected partner 1.4 (0.7– 2.6) .3666 0.79 (0.5– 1.1) .257 0.81 (0.63– 1.0) .132 0.43 (0.34– 0.57) <.0001
Sexual minority Commercial sex worker 3.0 (1.6– 5.8) .0008 1.8 (1.1– 2.8) .008 1.1 (0.84–1.5) .414 0.55 (0.44–0.70) <.0001
Man who has sex with men 1.6 (0.9– 2.9) .1331 1.2 (0.76–1.9) .405 1.0 (0.79–1.2) 1.000 0.80 (0.66–0.98) .037
Transgender person 2.2 (1.2– 4.2) .0135 1.2 (0.84–2.0) .248 1.3 (1.1– 1.6) .004 1.1 (0.50–1.3) .0247

Abbreviations: AIDS, acquired immune deficiency syndrome; ART, antiretroviral therapy; AOR, adjusted odds ratio; CI, confidence interval; MMT, methadone maintenance therapy.

*Compared with a person who acquired HIV from a main sexual partner; Bonferroni-corrected P value = .0014.