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. 2017 Apr 5;4(4):170050. doi: 10.1098/rsos.170050

Table 1.

Top 20 most frequent extracellular mutations in 9155 donors.

Chr Pos ID gene DNA mutation protein mutation mutation frequency
3 195505836 MU10935 MUC4 12615C>G H4205Q 44 out of 9155
1 29138975 MU68226 OPRD1 80G>T C27F 25 out of 9155
1 120611960 MU869951 NOTCH2 61G>A A21T 23 out of 9155
19 1065018 MU68245 ABCA7 6133G>T A2045S 18 out of 9155
15 22369378 MU4380351 OR4M2 803C>T S268F 16 out of 9155
17 37868208 MU85975 ERBB2 929C>T S310F 15 out of 9155
3 195509676 MU586249 MUC4 8775G>C Q2925H 15 out of 9155
7 55233043 MU589341 EGFR 1793G>T G598 V 15 out of 9155
3 195515449 MU605883 MUC4 3002T>A V1001E 14 out of 9155
19 9072091 MU4382243 MUC16 15355C>T P5119S 13 out of 9155
20 17639816 MU4585427 RRBP1 1337A>C Q446P 12 out of 9155
5 179071958 MU4110168 C5orf60 64G>C D22H 12 out of 9155
7 146829338 MU4413315 CNTNAP2 1085G>A G362E 12 out of 9155
1 158261127 MU4408485 CD1C 265C>T R89C 11 out of 9155
11 5345040 MU4383907 OR51B2 488C>T S163 L 11 out of 9155
17 21319519 MU613603 KCNJ12 865G>C E289Q 11 out of 9155
2 46707884 MU70561 TMEM247 458A>G Q153R 11 out of 9155
2 137814319 MU4440003 THSD7B 469G>A E157 K 11 out of 9155
3 195511286 MU4617526 MUC4 7165G>A D2389N 11 out of 9155
7 139167934 MU66261 KLRG2 455A>C K152T 11 out of 9155