Table 1.
Characteristics of the 90-patient cohort
| Characteristic | Number of patients/Median value (Range) | P* | |
|---|---|---|---|
| IMRT | VMAT | ||
| Diagnosis | 0.49 | ||
| Glioblastoma | 44 | 43 | |
| Oligodendroglioma | 1 | 0 | |
| Astrocytoma | 0 | 2 | |
| Tumor Location | 0.32 | ||
| Frontal | 14 | 23 | |
| Occipital | 2 | 1 | |
| Parietal | 8 | 6 | |
| Temporal | 13 | 6 | |
| Thalamus | 1 | 1 | |
| 2 or more lobes | 7 | 8 | |
| Tumor Side | 0.34 | ||
| Bilateral | 4 | 5 | |
| Left | 24 | 17 | |
| Right | 17 | 23 | |
| bPTV Volume (cc) | 85.1 (11.0–328.5) | 81.4 (28.3–285.3) | 0.94 |
| PTV Volume (cc) | 359.3 (128.9–779.1) | 370.8 (193.9–877.5) | 0.18 |
| Brain Volume (cc) | 1301.5 (1022.2–1849.0) | 1326.9 (1016.0–1658.6) | 0.23 |
| # Beams | <0.001 | ||
| 2 | 0 | 38 | |
| 3 | 0 | 7 | |
| 5 | 43 | 0 | |
| 6 | 2 | 0 | |
| # Couch Angles | <0.001 | ||
| 1 | 0 | 39 | |
| 2 | 0 | 6 | |
| 4 | 45 | 0 | |
| Multileaf Collimator | 0.02 | ||
| High Definition | 33 | 42 | |
| Standard | 12 | 3 | |
| # Monitor Units | 347 (285–487) | 453 (274–665) | <0.001 |
| Treatment Time | 15.0 (7.7–21) | 10.0 (6.3–15.3) | <0.001 |
IMRT intensity modulated radiation therapy, VMAT volumetric arc therapy, bPTV boost planning target volume prescribed to 60 Gy, PTV planning target volume prescribed to 50 Gy
*From Fisher’s exact test or Wilcoxon-Mann–Whitney rank sum analysis