Table 1.
Baseline characteristics of all patients
| ID | Age yrs | Sex | BMI kg/m2 | PaCO2
day, kPa |
PaO2 day, kPa | HCO3, day, mmol/L | PaCO2
night, kPa |
Δ PtCO2 night, kPa | LTOT l/min | FEV1 %pred | FEV1/FVC, % |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 57 | M | 34.7 | 5.8 | 8.8 | 27.0 | 7.6 | 2.5 | - | 23 | 34 |
| 2 | 74 | F | 28.0 | 6.3 | 9.3 | 28.6 | 7.0 | 2.8 | 2.0 | 39 | 52 |
| 3 | 53 | M | 21.4 | 6.1 | 7.7 | 28.3 | 6.5 | 1.3 | - | 28 | 38 |
| 4 | 70 | F | 27.2 | 6.4 | 8.4 | 27.2 | 6.8 | 5.3 | 4.0 | 35 | 68 |
| 5 | 67 | M | 35.9 | 7.1 | 9.3 | 36.0 | 7.3 | 2.2 | - | 50 | 66 |
| 6 | 82 | M | 21.5 | 8.6 | 5.9 | 31.9 | 10.6 | 0.8 | 2.0 | 30 | 63 |
| 7 | 78 | F | 31.6 | 7.6 | 7.8 | 30.6 | 9.6 | 1.5 | 2.5 | 29 | 51 |
| 8 | 74 | F | 22.5 | 7.8 | 10.9 | 30.6 | 8.0 | 2.5 | 3.0 | 36 | 61 |
| 9 | 68 | M | 19.4 | 7.3 | 8.8 | 28.6 | 6.9 | 2.7 | 4.0 | 36 | 40 |
| 10 | 63 | F | 22.8 | 7.4 | 8.6 | 29.3 | 8.2 | 1.3 | 3.0 | 18 | 39 |
| 11 | 71 | F | 25.1 | 5.9 | 9.6 | 27.0 | 7.4 | 2.6 | 1.0 | 35 | 66 |
| 12 | 63 | F | 27.8 | 8.1 | 8.7 | 28.4 | 8.8 | 4.6 | 3.0 | 37 | 61 |
| 13 | 60 | F | 18.3 | 9.4 | 7.1 | 38.5 | 8.8 | 1.9 | 3.0 | 11 | 38 |
| 14 | 77 | F | 18.7 | 6.4 | 10.2 | 28.0 | 7.5 | 1.0 | 2.0 | 41 | 49 |
| Mean | 68.7 | 25.2 | 6.8 | 8.9 | 29.3 | 7.0 | 2.3 | 34 | 53 | ||
| SD | 8.5 | 5.8 | 0.9 | 1.3 | 2.7 | 2.5 | 1.2 | 9 | 13 |
ID 7, 12 and 13 (italic) were excluded from analysis as they dropped out of the study. The mean and standard deviation (SD) of the 11 patients included in the full data set analysis are shown
BMI body mass index, PaO 2 partial arterial oxygen pressure in kilopascal (kPa), PaCO 2 partial arterial carbon dioxide pressure in kPa, HCO 3 − bicarbonate, Δ PtCO 2 increase in transcutaneous carbon dioxide pressure measured continuously at the ear lobe during the night; all blood gasses measured without NIV and with the regular amount of oxygen prescribed
FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity