Table 2.
Ventilatory settings, days needed to initiate NIV, and compliance rates of the study completers
| Ventilatory setting | LI-NIV | HI-NIV |
|---|---|---|
| IPAP, cm H2O, mean ± SD | 15.5 ± 1.1 | 23.6 ± 3.1 |
| EPAP, cm H2O, mean ± SD | 5.2 ± 0.6 | 5.4 ± 0.9 |
| BURR, breaths/min, mean ± SD | 11.6 ± 1.5 | 15.4 ± 0.8 |
| Supplemental oxygen, L/min, mean ± SD | 1.6 ± 1.3 | 1.4 ± 1.2 |
| Days needed to initiate NIV, median (range) | 2.7 (2–5) | 4.9 (2–10) |
| Number of hours used/day, median (range) | 4.2 (0.04–7.5) | 4.6 (0.11 to 9.2) |
| Percentage of days that NIV was used, % (range) | 63 (2–100) | 79 (2–100) |
| Mask, nasal, n (%))/oronasal, n (%)) | 3 (27)/8(73) | |
| Exhalation, vented mask (n (%))/active valve (n (%)) | 9 (82)/2 (18) | |
| Humidification, n (%) | 10 (90) | |
IPAP inspiratory positive airway pressure, EPAP expiratory positive airway pressure, BURR backup respiratory rate set on the ventilator, Supplemental oxygen connected to the ventilator, LI-NIV low-intensity NV, HI-NIV high-intensity NIV
Patient ID 12 and 13 only completed the HI-NIV period and were ventilated with higher IPAP (IPAP 31 and 28 cm H2O), but similar BURR