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. 2017 May 2;9:46. doi: 10.1186/s13148-017-0347-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — DNA methylation status of a colon cancer CIMP-specific five-gene marker panel in five CIMP-positive primary-metastasis pairs (a) and one pair with discordant CIMP status (b). Percent methylation reference (PMR) <4% is shown in white, 4 to 10% in light gray, >10 to 100% in dark gray, and >100% in black