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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Neuropharmacology. 2017 Feb 22;117:292–304. doi: 10.1016/j.neuropharm.2017.02.019

Fig. 4.

Fig. 4

Regulation of SERCA function by TSP4. A, Sample traces show the effect of inhibition of PMCA function with pH 8.8 Tyrode’s solution on neurons with and without TSP4 treatment. B, Summary data show effects of TSP4 on resting [Ca2+] i in pH 8.8 Tyrode’s solution. C, Sample traces show the effect of TSP4 on SERCA function, revealed by measuring recovery of the depolarization-induced transient recovery during inhibition of PMCA function with pH 8.8 Tyrode’s solution. Summary data show that TSP4 decreased SERCA functions in large-sized neurons (D), small-sized IB4neg neurons (E), and small-sized IB4pos neurons (F). Control data are from Fig. 2. * p < 0.05, ** p < 0.01, *** p < 0.001.