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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Neuropharmacology. 2017 Feb 22;117:292–304. doi: 10.1016/j.neuropharm.2017.02.019

Fig. 5.

Fig. 5

Regulation of ER Ca2+ store by TSP4. A, Sample traces show the effect of TSP4 on the Ca2+ transient induced by release of ER stores by caffeine (20 mM). B, Summary data show reduced releasable Ca2+ stores, measured as Ca2+ transient amplitude, in mouse neurons incubated in TSP4. C, Summary data show TSP4 effects in rat neurons. D, Sample traces show the effect of TSP4 on the Ca2+ transient induced by the release of stores by the SERCA blocker TG, 1 μM. E, Summary data show TSP4 suppresses the TG-induced Ca2+ transient amplitude. F, Summary data show TSP4 suppresses the TG-induced elevation of resting [Ca2+] i. * p <0.05, ** p < 0.01, *** p < 0.001.