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The Cavα2δ1 is required for TSP4’s regulation of recovery of the depolarization-induced Ca2+ transient. Sample traces (A,) and summary data (B) show that TSP4-induced increase of [Ca2+] i the recovery τ was eliminated in small-sized DRG neurons from Cavα2δ1 conditional KO mice. ** p < 0.01, *** p < 0.001.
