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. Author manuscript; available in PMC: 2018 Apr 20.
Published in final edited form as: Mol Cell. 2017 Apr 6;66(2):194–205.e5. doi: 10.1016/j.molcel.2017.03.003

Figure 4. Hypusine Is Required for Polypro-line Elongation In Vitro.

Figure 4

(A–D) Translation elongation kinetics for the following tripeptide motifs in the presence and absence of eIF5A and hypusination modification: (A) Phe-Phe-Phe (MFFFK), (B) Pro-Pro-Pro (MPPPK), (C) Pro-Asp-Ile (MPDIK), (D) Asp-Asp-Ile (MDDIK). Time points were quantified and reaction progression fitted to a single exponential. See also Figure S4.