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. 2017 May 2;16:74. doi: 10.1186/s12934-017-0683-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Scheme of alkane biosynthesis in engineered S. cerevisiae strains. The genes encoding fatty acyl-CoA oxidase, POX1, aldehyde dehydrogenase, HFD1 and alcohol dehydrogenase, ADH5, were disrupted (blue) and alcohol dehydrogenase was overexpressed (red). ADs were inserted in an episomal plasmid and they were expressed to convert fatty aldehydes to alkanes (green)