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. 2017 May 2;10:217. doi: 10.1186/s13071-017-2156-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Temporal genetic changes for P. vivax ama1 _I-II in southern Mexico from 1993 to 2011. a Nucleotide diversity (π) and genetic diversity (θ). b Linkage disequilibrium given by R². c Natural selection by dN-dS values. d Annual incidence of malaria according to confirmed cases in the 1993–2011 period within Jurisdiction VII of Chiapas