Table 4.
Univariate and multivariate analysis of prognostic factors for 30-day mortality
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Prognostic factors | OR | 95% CI | P value | OR | 95% CI | P value |
| Age | 1.04 | 1.02–1.06 | <0.001 | 1.04 | 1.02–1.07 | <0.001 |
| COPD | 2.03 | 1.38–2.97 | <0.001 | 1.77 | 1.13–2.76 | 0.01 |
| Malignancy | 1.94 | 1.16–3.26 | 0.01 | 2.25 | 1.25–4.06 | 0.007 |
| Body temperature (°C) | 0.65 | 0.55–0.77 | <0.001 | 0.81 | 0.67–0.99 | 0.045 |
| Heart rate (beats/min) | 1.01 | 1.00–1.02 | 0.004 | |||
| Respiratory rate (breaths/min) | 1.08 | 1.06–1.11 | <0.001 | 1.04 | 1.01–1.07 | 0.008 |
| PaO2/FiO2 ≤ 250 (mmHg) | 6.39 | 4.18–9.76 | <0.001 | 3.15 | 1.93–5.14 | <0.001 |
| Alb (g/dL) | 0.22 | 0.16–0.30 | <0.001 | 0.27 | 0.19–0.39 | <0.001 |
| BUN (mg/dL) | 1.03 | 1.02–1.04 | <0.001 | 1.01 | 1.00–1.02 | 0.04 |
| Cr (mg/dL) | 1.27 | 1.10–1.47 | 0.001 | |||
| Ht (%) | 0.95 | 0.92–0.99 | 0.004 | |||
| CRP (mg/L) | 1.04 | 1.02–1.06 | <0.001 | |||
| Multilobar pneumonia | 3.53 | 2.22–5.60 | <0.001 | |||
| Bacteremia | 4.39 | 2.58–7.49 | <0.001 | |||
| AZM combination | 0.42 | 0.23–0.77 | 0.005 | 0.50 | 0.26–0.97 | 0.04 |
| FQN combination | 6.55 | 4.10–10.5 | <0.001 | |||
| Mechanical ventilation | 7.93 | 5.16–12.2 | <0.001 | 2.99 | 1.75–5.12 | <0.001 |
| Vasopressor drug usage | 7.44 | 4.49–12.3 | <0.001 | |||
Abbreviations: Alb Albumin, AZM azithromycin, BUN Blood urea nitrogen, CI confidence interval, COPD chronic obstructive pulmonary disease, Cr Creatinine; CRP C-reactive protein, FiO 2 fraction of inspired oxygen, FQN fluoroquinolone, Ht Hematocrit, OR odds ratio, PaO 2 partial pressure of arterial oxygen