Table 5. Common nephrotoxic medication used in neonates .

Medication	Toxicity	Monitoring Strategies	Uses
Aminoglycosides	Nephro/ototoxic	Trough levels should be routinely monitored	Antibiotics
Ibuprofen	Nephrotoxic	Serum Creatinine and urine output should be normal before starting therapy	Used for treating PDA
Vancomycin	Nephrotoxic	Levels should be monitored	Antibiotics
Indomethacin	Nephrotoxic	Serum Creatinine and urine output should be normal before starting therapy	Used for treating PDA