Table 2. Summary of Lipid Subfraction Values.

	Baseline	18 month	Slope (%/month)	p-value (within group)	p-value (between groups)
Total Cholesterol (mg/dL)
Statins + Placebo	175 ± 42	153 ± 28	-0.6% (0.1%)	<0.001	0.84
Statins + Niacin	170 ± 36	150 ± 28	-0.6% (0.1%)	<0.001
LDL (mg/dL)
Statins + Placebo	93 ± 33	78 ± 20	-0.8% (0.2%)	<0.001	0.14
Statins + Niacin	88 ± 26	70 ± 21	-1.1% (0.2%)	<0.001
HDL (mg/dL)
Statins + Placebo	56 ± 17	53 ± 14	-0.3% (0.1%)	0.007	<0.001
Statins + Niacin	57 ± 16	62 ± 15	0.4% (0.1%)	0.0005
Triglycerides (mg/dL)
Statins + Placebo	133 ± 79	111 ± 50	-0.4% (0.3%)	0.10	0.03
Statins + Niacin	129 ± 84	90 ± 33	-1.3% (0.3%)	<0.001
non-HDL (mg/dL)
Statins + Placebo	119 ± 41	100 ± 23	-0.7% (0.2%)	<0.001	0.047
Statins + Niacin	113 ± 34	88 ± 23	-1.2% (0.2%)	<0.001
TC/HDL ratio
Statins + Placebo	3.3 ± 1.2	3.0 ± 1.2	-0.3% (0.1%)	0.02	<0.001
Statins + Niacin	3.2 ± 0.9	2.5 ± 0.5	-1.0% (0.1%)	<0.001

Means +/- SD. LDL denotes low density lipoprotein cholesterol. HDL denotes high density lipoprotein cholesterol. TC denotes total cholesterol. All values log-transformed for analysis of slopes over time; slopes presented as percent change per month.