Table 3. Summary of Imaging Endpoints.
Baseline volume mm3 | 18 month volume mm3 | Slope mm3/month or %/month | p-value (within group) | p-value (between groups) | |
---|---|---|---|---|---|
ICA Wall volume* | |||||
Statins + Placebo | 660 ± 230 | 590 ± 150 | -0.5% (0.2%) | 0.004 | 0.49 |
Statins + Niacin | 690 ± 240 | 590 ± 140 | -0.7% (0.2%) | 0.0002 | |
ICA Lumen | |||||
Statins + Placebo | 700 ± 280 | 700 ± 270 | -0.2 (0.9) | 0.81 | 0.98 |
Statins + Niacin | 720 ± 250 | 720 ± 250 | -0.2 (0.9) | 0.84 | |
ICA Lipid Core | |||||
Statins + Placebo | 47 ± 36 | 54 ± 42 | 0.2 (0.4) | 0.66 | 0.13 |
Statins + Niacin | 47 ± 37 | 33 ± 24 | -0.8 (0.5) | 0.10 | |
CC Wall volume* | |||||
Statins + Placebo | 110 ± 40 | 100 ± 20 | -0.1% (0.2%) | 0.52 | 0.26 |
Statins + Niacin | 120 ± 40 | 100 ± 20 | -0.4% (0.2%) | 0.03 | |
CC Lumen | |||||
Statins + Placebo | 140 ± 40 | 150 ± 40 | 0.05 (0.1) | 0.76 | 0.97 |
Statins + Niacin | 160 ± 40 | 160 ± 40 | 0.04 (0.2) | 0.80 |
log transformed.
Volumes are presented as means ± standard deviation. Values in parentheses represent standard error. ICA denotes internal carotid artery. CC denotes common carotid artery.