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. 2017 Apr 26;13:1181–1192. doi: 10.2147/NDT.S127094

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© 2017 Jiao et al. This work is published and licensed by Dove Medical Press Limited

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SAA treatment reversed spatial memory impairment in the MWM following cortical photothrombosis.

Notes: (A) The procedure for behavioral study (sham, n=9; Isch + Saline, ischemia control, n=9; Isch + SAA, ischemia treated with SAA, n=9). (B and C) The learning curves in MWM. (B) Latency to find the platform. (C) Velocity. (D–F) Probe test with the platform removed. (D) Latency to reach the platform area, (E) Amount of platform crossings. (F) Time spent in the target quadrant. (G) Visible platform training. Data are given as mean ± SEM. ^#P<0.05, ^##P<0.01, ^###P<0.001 (repeated-measures ANOVA); *P<0.05, **P<0.01, ***P<0.001 (one-way ANOVA or κ Independent Sample test).

Abbreviations: ANOVA, analysis of variance; MWM, Morris Water Maze; SAA, salvianolic acid A; SEM, standard error of the mean.