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. Author manuscript; available in PMC: 2017 May 3.
Published in final edited form as: J Comp Neurol. 2012 Aug 15;520(12):2630–2646. doi: 10.1002/cne.23056

Figure 6.

Figure 6

Effect of post-SCI administration of 17β-estradiol on skilled forelimb function. Skilled forelimb function was assessed by the vermicelli handling test. Quantification of the ipsilateral forepaw paw adjustments per piece at baseline (day 0) and on post-SCI days 7–49 are shown for the treatment groups. A: At baseline animals made 10–12 adjustments per pasta piece and animals in the Lam group continued to make this number of adjustments throughout the duration of the experiment. A significant decrease in the adjustments per piece on post-SCI weeks 1-7 was observed in the SCI group compared with the Lam (indicated by *). No significant differences in adjustments per piece were observed between the E2 0.5 group and the SCI only group. B: A significant increase in the adjustments per piece was observed in the E2 5.0 group as compared with the SCI group on post-SCI weeks 2–7 (indicated by **). Animals in the ICI group made significantly fewer adjustments per piece on post-SCI weeks 2–7 as compared with the E2 5.0 group (indicated by +). No significant differences between the SCI and ICI groups were observed. Note that data from Lam and SCI groups are duplicated from (A) for comparison.