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PELP1 has 11 LXXLL motifs for interactions with SRs, 2 proline-rich regions and PXXP domains for interactions with signaling proteins, a glutamic acid-rich carboxy region for interactions with histones. PELP1 also contains 2 cysteine-rich regions, which could possibly form zinc fingers for protein interactions, a nuclear localization signal (NLS), 3 nucleolar localization domains (NuLD), and a RIX1 domain.
