A, Immunohistochemical analysis of 5-μm paraffin sections of E18.5 and P1 pancreata for the presence of Myt3 (green), E-cadherin (red), and insulin/glucagon (blue). Yellow arrowheads indicate Myt3-positive cells with redistributed E-cadherin. White arrowheads mark Myt3-negative cells with E-cadherin distributed at their plasma membrane. B, Cells marked by arrowheads are shown at higher magnification, and signal intensity was measured along the blue line and is shown in the histograms beside each image. Scale bars, 10 μm.