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A, Stimulus coupled calcium influx in control-, shMyt3-, or Myt3-transduced, dispersed islets. B, Glucose-induced F-actin (red) redistribution in control-, shMyt3-, or Myt3-transduced, dispersed islets. Histograms represent signal intensity along a line segment (blue line) drawn through the cell. C, Glucose-stimulated insulin secretion in control-, shMyt3-, or Myt3-transduced whole islets cultured for 7 days.
