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. 2014 Jul 29;28(10):1656–1669. doi: 10.1210/me.2014-1117

Table 2.

Enriched signaling pathways of up-regulated genes with H3K27ac- or H3K4me3-increased regions by decidualization

Pathway Genes Benjamini P value P value
Type II diabetes mellitus IRS1, IRS2, INSR, PIK3CG, MAPK10, HK2 0.040308 8.23E-04
Insulin signaling pathway IRS1, IRS2, INSR, PIK3CG, MAPK10, FOXO1, AKT3, PRKAB2, HK2, 0.041218 0.001262
Aldosterone-regulated sodium reabsorption IRS1, IRS2, INSR, PIK3CG, SGK1, HSD11B1 0.042383 4.33E-04

Three pathways were identified as significantly enriched pathways in the up-regulated 230 genes with H3K27ac- or H3K4me3-increased regions by decidualization (KEGG pathway enrichment analysis).