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. 2014 Jun 30;28(8):1316–1328. doi: 10.1210/me.2014-1011

Table 3.

Analysis of ω-6 and ω-3 PUFAs Species in the Tail Samples

ω-6 PUFA Species, %
ω-3 PUFA Species, %
ω-6/ω-3 Ratio
LA AA DPA Total ω-6 ALA EPA DHA Total ω-3
WT RD 21.06 ± 0.16 2.55 ± 0.05 0.08 ± 0.00 23.72 ± 0.03 0.80 ± 0.01 0.17 ± 0.01 3.03 ± 0.02 4.52 ± 0.01 5.25 ± 0.01
fat-1 RD 19.57 ± 0.63a 0.19 ± 0.05a 0.03 ± 0.01 19.85 ± 0.63a 2.47 ± 0.17a 0.82 ± 0.14a 3.28 ± 0.09a 6.74 ± 0.58a 2.96 ± 0.28a
WT HFD1 4.47 ± 0.27 1.57 ± 0.23 0.03 ± 0.01 6.14 ± 0.15 0.41 ± 0.06 0.10 ± 0.01 1.57 ± 0.11 2.24 ± 0.12 2.74 ± 0.24
fat-1 HFD1 1.86 ± 0.13a 0.04 ± 0.01a 0.01 ± 0.00 1.94 ± 0.55a 0.73 ± 0.11a 0.70 ± 0.15a 2.20 ± 0.43a 3.75 ± 0.45a 0.52 ± 0.17a
WT HFD2 21.31 ± 0.60 4.07 ± 0.44 0.16 ± 0.02 25.58 ± 0.55 0.25 ± 0.02 0.09 ± 0.03 1.62 ± 0.13 2.32 ± 0.13 11.04 ± 0.68
fat-1 HFD2 19.01 ± 0.54a 0.18 ± 0.03a 0.01 ± 0.00a 19.20 ± 0.54a 2.46 ± 0.46a 0.94 ± 0.03a 2.13 ± 0.13a 6.63 ± 0.37a 2.90 ± 0.20a

Abbreviations: ALA, α-lipoic acid; DHA, docosahexaenoic acid; DPA, docosapentaenoic acid; LA, linoleic acid. Compositions of ω-6 or ω-3 PUFAs were expressed using relative percentages, ie, the distribution areas of ω-3 or ω-6 PUFA peaks divided by the total peak areas of all detectable saturated and unsaturated presented are means ± SD; n = 6.

a

P < .01 when the fat-1 group was compared with the WT control group.