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. 2016 May 11;22(6):497–510. doi: 10.1016/j.molmed.2016.04.007

Figure 3.

Figure 3

Key Figure: The Yin–Yang of PTX3 in Innate Immunity, Inflammation, Tissue Damage, and Cancer

Depending on the tissue context, cellular source, and levels of production, PTX3 can either play a protective role in a host or contribute to impaired cell/tissue homeostasis and disease pathogenesis. Abbreviations: CRI, cancer-related inflammation; HA, hyaluronic acid; FG, fibrinogen; Plg, plasminogen.