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. Author manuscript; available in PMC: 2017 May 3.
Published in final edited form as: Biochim Biophys Acta. 2016 Feb 18;1862(6):1111–1121. doi: 10.1016/j.bbadis.2016.02.007

Figure 8. Effects of Cx43 ablation on APAP-induced inflammation.

Figure 8

WT and Cx43+/- mice (n = 5-10) were overdosed with 300 mg/kg APAP followed by sampling at different time points (i.e. after 0, 1, 6 and 24 hours). ELISA analyses of IL-1β, IL-6, IL-10, IFNγ and TNFα were performed in liver (upper panels) and serum (lower panels) samples. Data are expressed as means ± SEM with **p ≤ 0.01 and ****p ≤ 0.0001 compared to WT animals at indicated time points.